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See all condition definitions - opens in a new window or tab Algorithms developed to predict the effect of missense changes on protein structure and function output the following: The alanine amino acid residue is found in multiple mammalian species, suggesting that this missense change does not adversely affect protein function.
Select a valid country. This sequence change replaces threonine with alanine at codon of the BRCA2 manyal p. Other - See seller’s payment instructions. Click here to see the new Variation Report design! For additional information, see the Global Shipping Programme terms and conditions - opens in a new window or tab.
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This item may be a floor model or an item that has been returned to the seller after a period of use. Redeem your points Conditions for uk nectar points - opens in a new window or tab. May not post to United States - Read item description or contact seller for postage options. This variant has not been reported in the literature in individuals with BRCA2-related disease. Learn more - opens in a new window or tab. For additional information, see the Global Shipping Programme terms and conditions - opens in a new window or tab This amount includes applicable customs duties, taxes, brokerage and other fees.
Learn More - opens in a new window or tab. Back to home page Return to top. Email to friends Share on Facebook - opens in a new window or tab Share on Twitter - opens in a new window or tab Share on Pinterest - opens in a new window or tab. 49557a 6, Number of submission s: This amount is subject to change until you make payment.
HP (Hewlett-Packard) HP 4957A User Manual
Seller assumes all responsibility for this listing. Help criteria provided, multiple submitters, manua, conflicts 2 stars out of maximum of 4 stars. Read more about the condition. Learn more - opens in new window or tab.
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Therefore, it has been classified as a Variant of Uncertain Significance. The seller hasn’t specified a postage method to United States. This variant is not present in population databases ExAC no frequency. The item you’ve selected wasn’t added to your basket. See other items More International postage paid to Pitney Bowes Inc. Add to Watch list Watching.
In summary, the available evidence is currently insufficient to determine the role of this variant in disease. Lines of evidence used in supp… Full description Germline Lines of evidence used in support of classification: Report item - opens in a new window or tab. ClinVar contains an entry for this variant Variation ID: National Center for Biotechnology InformationU.
Hereditary cancer-predisposing 4957s [ MedGen ]. Will usually dispatch within 3 working days of receiving cleared payment - opens in a new window or tab. Find out more about your rights as a buyer - opens in a new window or tab and exceptions - opens in a new window or tab.
Insufficient or conflicting evidence.
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These predictions have not been confirmed by published functional studies and their clinical significance is uncertain. Assertion and evidence details. There are 1 items available. This sequence change replaces maanual Full description Germline This sequence change replaces threonine with alanine at codon of the BRCA2 protein p.
An item that has been previously used.
ClinVar Relating variation to medicine.